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phenobarbital will decrease the level or impact of stiripentol by influencing hepatic enzyme CYP1A2 metabolism. Avoid or Use Alternate Drug. If unable to steer clear of coadministration of stiripentol with potent CYP1A2 inducers, improve stiripentol dose.Use in Pregnancy. Barbiturates can cause fetal harm when administered into a pregnant girl. Ret